Monodispersed Micro and Nanospheres: Fabrication of Collagen-based Reservoir Systems
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چکیده
Galway, Ireland Monodispersed Micro and Nanospheres: Fabrication of Collagen-based Reservoir Systems Gianluca Fontana, Shane Browne, Hongliang Cao, Mohammad Abu-Rub, Dimitrios Zeugolis, Wenxin Wang, Abhay Pandit* Network of Excellence for Functional Biomaterials, National University of Ireland Galway *[email protected] Introduction One important aspect in tissue engineering is the release of bioactive factors. Therefore, the loading properties of the delivery system can be a determinant for the bioactivity. The hypothesis behind this study is that a reservoir system which has a spherical shape that has the optimal surface/volume ratio can be developed using a template fabrication method. The overall objective of this work was to identify a method that allows tight size control over the spheres with high efficiency and reproducibility. This study highlights the comparison of different methods.
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